Biostatistician / Computational Biologist in Statistical Genetics of Complex Eye Diseases
We are seeking a highly qualified and motivated Biostatistician or Bioinformaticist to join our collaborative and interdisciplinary team in the Ocular Genomic Institute (OGI) and Department of Ophthalmology at Massachusetts Eye and Ear (MEE). MEE is a teaching hospital of Harvard Medical School, and an international leader for treatment and research in Ophthalmology and Otolaryngology. The candidate will work on innovative projects that combine human genetics, functional genomics, and statistical learning to uncover novel genetic and biological causes of common eye diseases, including diabetic retinopathy and steroid-induced ocular hypertension, and differential response to drug treatments.
The successful candidate should have a PhD in Biostatistics, Statistical Genetics, Computational Biology, Bioinformatics, Computer Science, or a related quantitative field, and strong programming skills, and should be excited to contribute to advancing the science and medicine of eye disease. Experience in large-scale data analysis, preferably genomic or next-generation sequencing (NGS), required. Research projects will include statistical analyses of genome-wide association studies (GWAS), whole genome and whole exome sequencing data, pharmacogenetic studies, and integration of genetic associations with functional genomic data, to identify novel genetic risk factors and biological processes associated with complex eye diseases and drug treatment response.
The candidate will work under the supervision of Dr. Ayellet Segre (, a statistical geneticist, and Dr. Lucia Sobrin, a clinician scientist () at MEE. Being a member of our groups will provide the applicant with the opportunity to contribute to clinically impactful projects and large collaborative efforts in the field of genomics and common eye diseases, and to present at local, national, and international meetings. To learn more about the OGI please visit: .
If interested, please send your CV, cover letter describing your previous research experience and future research interests, and contact information for 3 references to Dr. Ayellet Segre: email@example.com, and Dr. Sobrin: firstname.lastname@example.org.
Please contact in addition to applying with the link below if you are interested in applying for this position.
Education and Experience Qualifications
The Segre and Sobrin labs are located in the main hospital building of Mass Eye and Ear (MEE), 243 Charles Street, in standard research and office work spaces of the Ocular Genomics Institute at MEE, with convenient access to the MEE cafeteria on the 7th floor. The candidate will work amongst a vibrant team of computational biologists, biostatisticians, research assistants, and students in the Ocular Genomics Institute, and will be part of a larger multidisciplinary research environment, which includes geneticists, experimental biologists, and clinical scientists. There will be abundant opportunities to interact with the Medical and Population Genetics community at the Broad Institute of Harvard and MIT, and with national and international collaborators. Given the ongoing COVID19 pandemic, work will be hybrid with both remote and in-person components.
Massachusetts Eye and Ear is an affirmative action/equal opportunity employer.EEO Statement
Massachusetts Eye and Ear is proud to be an equal-opportunity employer and is committed to providing a workplace free from harassment or discrimination. All employment decisions are made without regard to race, color, age, gender, gender identification, sexual orientation, religion, marital status, sex, pregnancy or conditions related to pregnancy, national origin/ancestry, citizenship, disability, military status, genetic information, or any other basis prohibited by law. These protections extend to all management practices and decisions, including recruitment and hiring practices, appraisal systems, promotions, training, and career development programs.