Research Fellow- Molecular Genetics of Neural Development
Boston, MA 
Posted 28 days ago
Job Description

A postdoctoral Research Fellow position is available in the Shrestha Laboratory at Mass Eye & Ear / Harvard Medical School. Our lab studies the molecular genetic bases of neural development and function in the auditory system with an emphasis on neuronal subtype-specific contributions to sound sensation and perception.

Building on our recent discovery that spiral ganglion neurons (SGNs) in the cochlea exhibit activity-dependent plasticity in molecular identities, we aim to derive a mechanistic understanding of how neuronal subtype-specific gene expression programs arise during development. Toward that end, we are leveraging single-cell technologies (scRNA-seq, scATAC-seq) and mouse genetics to delineate the regulatory logic influencing cell fate trajectories in the auditory periphery. This position offers an excellent opportunity to learn and apply these cutting-edge technologies in an inclusive, supportive training environment.

Further information about our laboratory can be found at

Relevant publication:

Shrestha et al., Sensory Neuron Diversity in the Inner Ear Is Shaped by Activity, Cell, 2018



PhD in Neuroscience, Cell Biology, Genetics, or any related discipline. Candidates with an MD and substantive wet lab research experience may also be considered. Prior experience in single-cell genomics a big plus, but not required.

EEO Statement

Mass Eye and Ear is an Affirmative Action Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.

Primary Location: MA-Boston-MEI Mass Eye and Ear Main Building Boston
Work Locations:
MEI Mass Eye and Ear Main Building Boston
243 Charles Street
Boston 02114
Job: MD/PHD/Fellows/ PostDocs
Organization: Mass. Eye and Ear (MEE)
Schedule: Full-time
Standard Hours: 40
Shift: Day Job
Employee Status: Regular
Recruiting Department: MEI Otolaryngology
Job Posting: Jan 31, 2022

Massachusetts Eye and Ear is proud to be an equal-opportunity employer and is committed to providing a workplace free from harassment or discrimination. All employment decisions are made without regard to race, color, age, gender, gender identification, sexual orientation, religion, marital status, sex, pregnancy or conditions related to pregnancy, national origin/ancestry, citizenship, disability, military status, genetic information, or any other basis prohibited by law. These protections extend to all management practices and decisions, including recruitment and hiring practices, appraisal systems, promotions, training, and career development programs.


Job Summary
Start Date
As soon as possible
Employment Term and Type
Regular, Full Time
Required Education
Required Experience
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