Senior Scientific Researcher/Antibody Engineering, Genentech Research
South San Francisco, CA US
Posted 1 day ago
Job Description

The Position

We are seeking a highly motivated Senior Scientific Researcher to join the Department of Antibody Engineering. The successful candidate will work in the development of new antibodies for therapeutic and research applications using molecular biology and protein engineering approaches. The position also has a strong emphasis on developing new technologies for antibody discovery, optimization and engineering using antibody phage display and Next-Gen sequencing of immune and synthetic repertoires. The individual is expected to work in a highly collaborative environment, demonstrate initiative in solving difficult technical challenges and to work simultaneously in multiple projects.

For more information, please see Isidro Hotzel's Sr. Scientist profile on

Who You Are

Requirements include an MS or PhD degree in biochemistry, molecular biology or related discipline with 5 years (MS) or 3 years (PhD) of relevant research experience.

Successful candidates will have expertise in molecular biology, including cloning and mutagenesis, familiarity with concepts of protein biochemistry and structural biology and computational skills for analysis of large datasets.

Experience with protein/antibody engineering and directed evolution methods such as phage display or related methods and analysis of protein interactions by surface plasmon resonance (Biacore) and related methods is a plus. Qualified candidates will have demonstrated ability to rapidly and independently become proficient in new and diverse experimental techniques and have strong oral and written communication skills. Excellent organizational, experimental data recording and time management skills are also required.


Roche is an Equal Opportunity Employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status.


Job Summary
Start Date
As soon as possible
Employment Term and Type
Regular, Full Time
Required Education
Required Experience
3 to 5 years
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